The ZDSD Rat – A model of Metabolic Syndrome

Characteristics

  • Early onset of polygenic obesity  in the absence of high caloric diets by two months of age
  • Hyperphagia
  • Spontaneous diabetes starting at about 4 months of age
  • Metabolic syndrome characteristic such as
    • Hypertension
    • Insulin resistance and glucose intolerance
    • Elevated cardiovascular markers
    • Dyslipidemia
  • Diabetic co-morbidities such as nephropathy and osteoporosis and wound healing

Full Study Data & Presentation – Instant Access

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Health Reports

PreClinOmics Health Monitoring Program

ZDSD Health Report


Study Data

Download PDF containing all slides listed below here.

Onset of Diabetes

Body Composition

Insulin Sensitivity

Reference Compound Efficacy

Bone

Serum Markers of Metabolic Disease

Diabetic Nephropathy /Serum Markers of Renal Disease

Serum Markers of Vascular Disease

Serum Markers of Inflammation


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